MACERATION AND PERCOLATION PDF

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The key difference between maceration and percolation is that the maceration is the process of soaking or steeping something to make it soft. Various Methods of Extraction • Maceration • Percolation • Infusion • Decoction • Digestion; 9. Purposes of Extraction • The sole purpose of. Read 1 answer by scientists to the question asked by Mustafa Saddam on Dec 4,

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The marc can be squeezed out of a fine muslin piece, when the quantity of the drug is very small. Once material has passed through the boundary layer, mass transfer takes place by bulk movement of the solution, known as eddy diffusion.

Thus prolonged comminution size reduction will produce heat percolafion may damage the heat labile constituents of the drug. Dry extract – obtained by completely removing the solvent under reduced pressure.

However, their applications differ from andd other. The drug is allowed to stand for few days. Concentrated infusion of orange. Continuous hot extraction process should not be used for those drugs containing thermolabile active macceration.

Concentrated compound infusion of gentian. Since there is no limit to the vigor of the movement of the bulk of the fluid, so the rate controlling step is the molecular diffusion.

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Concentration of the product. The key target of the process of maceration is to make the substance, on which liquid is applied, softer than before.

Infusion, Decoction, Expression, Maceration, Percolation

Volume of menstruum required for second maceration. Tests to check complete exhaustion of the drug:. Percilation container is generally taken to reduce the loss of solvents by evaporation.

Multiple maceration process is carried out in the same way as simple maceration process, but the menstruum used is divided into two parts in double maceration process and three parts in triple maceration process.

Water is used as menstruum and the drug, cut in small pieces, is boiled with the menstruum for 10 to 15 minutes. Maceration is a soaking method by which the substances are softened and extracted into a liquid while percolation is a brewing method in which anx liquid runs through a filter with the dried and grounded compound.

Later the water is filtered. When the liquid begins to drip from the bottom of the percolator, the tap fitted at its bottom is closed. What is Maceration 3. Therapeutic value of the drug. The transport of molecules will take place in two stages:. Difference in the volume and the volume used represents the volume retained by the weighable quantity of the drug percolatio. Decoction is the process in which the water soluble and heat stable constituents of hard and woody crude drugs are extracted out.

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Comparison between extraction method: Maceration makes substances softer than before they were while percolation makes liquid drain through pores downwards.

Hence the inflammability of a solvent is very important from the point of view of industry. During this period, shaking is done occasionally. Before drying the fresh drugs are surrounde by a thin film of water. Percolation process for concentrated preparations.

Infusion, Decoction, Expression, Maceration, Percolation

Cost of the drug. The marc left is a compact gummy matter. On the other hand, percolation involves filtration through a porous material. Fresh infusion of Quassia. This process is a modified form of maceration where the drug is extracted by heating at a particular pressure.

To penetrate the cell wall the solvent must have to displace the air first. Give the description briefly with diagram. It consists of a loose perforated shelf resting on a projection near the top of the pot.

Water as a solvent for extraction: Volume of menstruum required for first maceration. Maceration of Swedish Liqueur. Especially, rainfall seeps underground via the percolation.

Introduction to Pharmaceutics – A.