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Dermatol Clin. Jul;11(3) Epidermolysis bullosa acquisita and bullous systemic lupus erythematosus. Diseases of autoimmunity to type VII collagen. Bullous Systemic Lupus Erythematosus (BSLE) is a rare manifestation of . (BP), inflammatory variant of epidermolysis bullosa acquisita (EBA), and linear IgA. However, unlike epidermolysis bullosa acquisita, bullous systemic lupus erythematosus tends to respond dramatically to treatment with.

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Lupus Eritematoso Sistémico Bulloso en una niña de 10 años de edad. Reporte de un caso

Se continuar a navegar, consideramos que aceita o seu uso. Bullous systemic lupus erythematosus with milia and calcinosis.

Bullous Systemic Lupus Erythematosus: J Invest Dermatol ; This article also discusses the epidemiology, clinical, histopathologic and immunopathologic features, differential diagnosis and the treatment of BSLE. Derechos de autor Biociencias. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

Int J Dermatol ; J Invest Dermatol, 91pp. Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: Report of two cases and a review of the literature. Concurrent painful oral ulcers were reported; though, other mucosae were uninvolved. The cutaneous pathology of lupus erythematosus: Clinical, features, course, and outcome in patients with lateonset disease.


Am J Clin Dermatol ; Bullous systemic lupus erythematosus: J Am Acad Dermatol, 22pp. Russell’s viper venom test revealed no lupus like anticoagulant. Int J Dermatol, 31pp.

Autoantibody mediated pathomechanisms regulate clinical-pathological phenotypes of acquired bullpso and bullous SLE. Our understanding of the pathology of this interesting and unique dermatologic condition has evolved with improved diagnostic criteria and clinicohistologic profiling. William Stohl et al.

Bullous systemic lupus erythematosus with antibodies recognizing multiple basement membrane components, bullous pemphigoid antigen1, lamini-5, laminin-6, and bullosk VII collagen.

Most reported cases have dramatically responded to dapsone, with cessation of new lesions in days and luphs within several days. Vibeke Strand et al. Bullous systemic lupus erythematosus with cutaneous mucinosis and leukocytoclastic vasculitis.

Occasionally other antigens such as laminin 5, laminin 6, and BP bullous pemphigoid antigen have also been described. On examination, there were multiple, tense, clear as well as hemorrhagic, vesicles and bullae, arising over an erythematous base and predominantly involving upper body [ Figure 1 ].

The course of the disease is benign with remission reported in most of the pupus within a year, including ours.

Lupus Eritematoso Sistémico Bulloso en una niña de 10 años de edad. Reporte de un caso

Lu;us Clin Immunol ; Even if one is not able to initiate dapsone due to relative contraindications, as in our case, every effort should be made to use it as early as possible. J Am Acad Dermatol, 9pp.


Also, the dramatic response to dapsone is highlighted which remains the drug of choice in the management of this disorder. Our patient showed only modest improvement on steroids and antimalarials, complete response being seen only with dapsone. Bullous skin disease lulus lupus erythematosus.

Lihua Duan et al. Hematinics were also initiated. Systemic lupus erythematosus with vesiculobullous lesions. Other bullous disorders such as bullous lu;us, epirdermolysis bullosa acquisita, linear IgA bullous dermatosis and dermatitis herpetiformis has also been reported in association with SLE.

Epidermolysis bullosa acquisita occurring in association lupjs bullous lupus erythematosus. Autoantibodies to type VII collagen have heterogeneous subclass and light chain compositions and their complement-activating capacities do not correlate with the inflammatory clinical phenotype. Extensive serological workup revealed antinuclear antibody positivity of 1: Concomitant lupus nephritis and bulous eruption in systemic lupus erythematosus.