Klaricid IV mg (PL /, Abbott Laboratories Ltd). No new or unexpected safety concerns arose from this application and it was therefore judged that. Indications, side effects, contraindications and other prescribing information for Klaricid IV on MIMS. Clarithromycin is indicated in: Lower respiratory tract infection: acute and chronic bronchitis and pneumonia;; Upper respiratory tract infection: sinusitis and.
If you notice other side-effects not listed above, contact your doctor for medical advice. Concomitant administration of clarithromycin and ergot alkaloids e.
CLARITHROMYCIN | Drug | BNF content published by NICE
To view the changes to a medicine you must sign up and log in. The microbiologically active metabolite hydroxyclarithromycin is formed by first pass metabolism as indicated by lower biovailability of the metabolite following IV administration.
Consult your doctor for advice on alternative medicines. There was no significant difference in the incidence of these gastrointestinal adverse reactions during clinical trials between the patient population with or without pre-existing mycobacterial infections. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
Co-administration of clarithromycin with klariicd, tadalafil or vardenafil would likely result in increased phosphodiesterase inhibitor exposure.
Subscribe to receive email notifications whenever new articles are published. Possible side effects 5. Children older than 12 years: Psychotic disorder, confusional state 5depersonalisation, depression, disorientation, hallucination, abnormal dreams, mania.
Possible side effects Like all medicines, Klaricid IV can cause side effects although not everybody gets them. Klaricid IV mg does not contain tartrazine or other azo dyes, lactose or gluten. Body weight under 8 kg: Localized infections due to Mycobacterium chelonae, Mycobacterium fortuitum, or Mycobacterium kansasii Pack Size: Patients taking oral contraceptives should be warned that if diarrhoea, vomiting or breakthrough bleeding occur there is a possibility of contraceptive failure.
One patient who had a history of bipolar disorder ingested 8 grams of clarithromycin and showed altered mental status, paranoid behaviour, hypokalaemia and hypoxaemia.
We comply with the HONcode standard for trustworthy health information – verify here. Reduction of sildenafil, tadalafil and vardenafil dosages should be considered when these drugs are co-administered with clarithromycin. Other side effects Common side effects may affect up to 1 klaticid 10 people include; inflammation, tenderness or pain at the site of the injection difficulty sleeping changes in sense of taste headache widening of blood vessels stomach problems such as feeling sick, vomiting, stomach pain, indigestion, diarrhoea increased sweating Uncommon side effects may include up to 1 in people include: Klaricid IV is given to you slowly through a needle, into your vein over a period of at least an hour.
These are signs that your liver may have inflammation and not be working properly. Vials are packed in units of 1, 4 and 6.
Klarickd of clarithromycin, known to inhibit CYP3A, and a drug primarily metabolised by CYP3A may be associated with elevations in drug concentrations that could increase or prolong both therapeutic and adverse effects of the concomitant drug.
This includes any possible side effects not listed in the leaflet. Usually, government’s categorizes medicines that can be addictive as controlled substances.
Liver function test abnormal. Because clarithromycin appears to interfere with the absorption of simultaneously administered oral zidovudine, this interaction can be largely avoided by staggering the doses klricid clarithromycin and zidovudine to allow for a 4-hour interval between each medication.
Cardiac arrest 1atrial fibrillation 1electrocardiogram QT prolonged, extrasystoles 1palpitations. Klaricid IV is used whenever an intravenous injection into the vein antibiotic is required to treat severe infections or, alternatively, if a patient cannot swallow Klaricid tablets.
Do not pass it on to others. Use Klaricid Paediatric Suspension. Therefore, children under 12 years of i should use clarithromycin paediatric suspension.
Method klsricid administration Refer to the summary of product characteristics for posology information.
Sildenafil, tadalafil and vardenafil Each of these phosphodiesterase inhibitors is metabolised, at least in part, by CYP3A, and CYP3A may be inhibited by concomitantly administered clarithromycin. It exerts its antibacterial action by selectively binding to the 50s ribosomal sub-unit of susceptible bacteria preventing translocation of activated amino acids.
This may result in QT prolongation and cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation and torsades de pointes. View All Brand Names of this Generic. What you need to know before receiving Klaricid IV 3. Therefore, caution should be exercised in administering this antibiotic to patients with impaired klzricid function. Dose reduction may need to be considered. Klaricid belongs to a group of medicines called macrolide antibiotics.