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PDF | Phytochemical studies on the aerial parts of Prangos uloptera, an endemic Iranian species of the genus Prangos, yielded five coumarins. Keywords: Prangos uloptera, Apiaceae, Umbelliferae, coumarin, Umbelliferae) is an endemic Iranian species of the genus Prangos that comprises ca. Antimicrobial and antioxidant activities of coumarins from the roots of Ferulago campestris (Apiaceae). Basile A(1), Sorbo S, Spadaro V, Bruno.

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Foeniculum vulgare has shown some activity agains the Tuberulosis, including some of the drug resistant strains. Coumarins from Cnidium monnieri and their antiosteoporotic activity.

Penetration kinetics of xanthotoxin across human skin and stratum corneum. Angelica has also been credited with enhancing the immune system, which helps the body fight off disease, as well as anti-tumor activity. Hormonal effects are also noted from many Apiacea plants — from the historical folkloric use of Fennel and Anise seed tea to promote lactation in nursing women, to the modern research on Apiacea compounds and gonadotropins activity in the central nervous system.

Research has been conducted on consuming parsley as a food to determine whethter or not the apigenin was absorbed and able to be assimilated in away that may have biologicial effects.

The oral consumption of Foeniculum has shown some efficacy in relieving dysmenorrhea in young women. Xanthotoxin is reported to be reasonably well absorbed and to be retained in the stratum apiaecae for 24 hours.

Investigations into Foeniculum vulgare toxicity have shown no teratogenicity. Coumarin compounds have also shown activity against renal cell carcinoma. Ammi visnaga has been used traditionally to facilliatate the passage of renal calculi.


When plants and light affect the skin”. The seeds of these species are particularly high in these compounds. The Apiaceae family apiaceas includes a smaller number of poisonous species, including poison hemlockwater hemlockand fool’s parsley.

Similar findings have been reported by other researchers. Apiaceae Coumarin and Vascular Effects Coumarins from Angelica species have been noted to posess platelet anti-aggregating effects either equal to or greatly surpassing that of aspirin. Therefore, the Umbells are not fiery, are not earthy, and are not particularly watery. Plant photosensitizers with antiviral properties.

Antiviral screening of British Columbian medicinal plants. Apium graveolans is noted apiacwae reduce cholesterol without interfering with general metabolism of hepatic sterols. Platelet anti-aggregant property of some Moroccan medicinal plants. The family is most abundant in the northern hemisphere, though can be found worldwide.

Effect of osthol apiaceaee total coumarins of fructus cnidii on thyroid hormone and thyrotropic hormone in kidney-yang deficiency rats. The phototoxicity of 8-methoxythionepsoralen and 6-methylthionecoumarin. Researchers showed that administration of these coumarins could prevent suppression of adrenal function in animals given cortisone. The ripe seeds of the wild carrot were reportedly used by Native American peoples as an agent to reduce fertility.

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Phytochemical studies on the aerial parts of Prangos ulopteraan endemic Iranian species of the genus Prangosyielded five coumarins, xanthotoxin 1prangenin 2scopoletin 3deltoin 4 and prangolarin 5. Generally, all members of this family are best cultivated in the cool-season garden; indeed, they may not grow at all if the soils are too warm.

The black swallowtail butterfly, Papilio polyxenesuses the Apiaceae family for food and host plants for oviposition. Effect of parsley Petroselinum crispum Mill. Via nitric oxide pathways, Cnidium has general vasodilating and blood moving effects making this plant, like other Apiacea members appropritate for hypertension and all manner of vascular diseases. Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats.


Osthol, but not xanthotoxin has been noted to have activity at TRH receptors in rats. Cloning of bergaptol O-methyltransferase. Journal of Agricultural and Food Chemistry. Influence of umbelliferone on membrane-bound ATPases in streptozotocin-induced diabetic rats. Estrogen and other hormones are increasingly being explored for their effects on neurotransmission in the central nervous system.

Coumarins and gamma-pyrone derivatives from Prangos pabularia: The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats. Bergapten and xanthotoxin are considered to be methoxylated psoralens and are the final products of furanocoumarin biosythesis common in both Apicacea and Rutaceae families. Many species in the Apiaceae family produce phototoxic substances called furanocoumarins that sensitize human skin to sunlight.

The fruits of many species are dispersed by wind but others such as those of Daucus spp.

Coumarins from the aerial parts of Prangos uloptera (Apiaceae)

Osthole increases glycosylation of hepatitis B surface antigen and suppresses the secretion of hepatitis B virus in vitro. Yale J Biol Med. Comparative screening of plant essential oils: Phototoxic coumarins in limes.

J Agric Food Chem. Other research suggests that a multiple active compounds in Apium lower triglycerides and cholesterol via a variety of mechanisms.