Insulin lispro protamine is used to reduce high blood sugar levels in patients Insulin lispro protamine is injected under the skin. Humalog Mix KwikPen. HUMALOG é indicado no tratamento de pacientes com diabetes mellitus que necessitam .. médico e leve a embalagem ou bula do medicamento, se possível. 18 abr. B. Humalog Mix 50 Lilly (50% lispro/protamina e 50% lispro). 2,0. .. dicado em bula, o uso combinado de exanatide com.
The use of dosages which are lixpro or discontinuation of treatment, especially in insulin-dependent diabetics, may lead to hyperglycaemia and diabetic ketoacidosis; conditions which are potentially lethal.
Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen. The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual.
This condition usually resolves in a lisro days to a few weeks. Therefore, the requirement for patients to self-inject is that they can read the dose counter on the pen. Mild hypoglycaemic episodes will respond to oral administration of glucose or other sugar or saccharated products. The reduction of HbA1c would also be expected with other insulin products e. However, glucose solution must be given intravenously if glucagon is not available or if the patient fails to respond to glucagon.
Conditions which may make the early warning symptoms of hypoglycaemia different or less pronounced include long duration of diabetes, intensified insulin therapy, diabetic nerve disease or medicinal products such as beta-blockers.
Humalog 200 Units/ml KwikPen, solution for injection in pre-filled pen
Enter medicine name or company Start typing to retrieve search suggestions. Humalog can be used in conjunction with a longer-acting insulin or oral sulphonylurea medicinal products, on the advice of a physician. To email a medicine you must sign up and log in.
Last updated on eMC: Transferring a patient to another type or brand of insulin Transferring a patient to another type or brand of insulin should be done under strict medical supervision. Uncorrected hypoglycaemic or hyperglycaemic reactions can cause loss of consciousness, coma, or death.
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Severe cases of generalised allergy may be life-threatening. No specific frequency for hypoglycaemia is presented, since hypoglycaemia is a result of both the insulin dose and other factors e. Time to maximum concentration was also similar lisppro formulations. Humalog should not be used if it appears cloudy, thickened, or slightly coloured or if solid particles are visible.
A10AB04 The primary activity of insulin lispro is the regulation of glucose metabolism. Type I glass cartridges, sealed with halobutyl disc seals and plunger heads and secured with aluminium seals. Insulin lispro maintains more rapid absorption when compared to soluble human insulin in patients with renal impairment. Before using the KwikPen the user manual included in the package leaflet must be read carefully.
The number of insulin units is shown in the dose window of the pen regardless of strength and no dose conversion should be done when bila a patient to a new strength lisprl to a pen with a different dose step.
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Huamlog trials in patients with type 1 and type 2 diabetes have demonstrated a reduced number of episodes of nocturnal hypoglycaemia with insulin lispro compared to soluble human insulin. Hypoglycaemia is the most frequent adverse reaction of insulin lispro therapy that a patient with diabetes may suffer. It was first approved for use in the United States inmaking it Yellow Card Scheme, website: If the combination is used, patients should be observed for signs and symptoms of heart failure, weight gain and oedema.
Skin and subcutaneous tissue disorders. In in vitro tests, including binding to insulin receptor sites and effects on growing cells, insulin lispro behaved in a manner that closely resembled human insulin.
Company contact details Eli Lilly and Company Limited. Qualitative and quantitative composition 3. The time course of insulin lispro action may vary in different individuals or at different times in the same individual lisprk is dependent on dose, site of injection, blood supply, temperature and physical humalg.
When necessary Humalog can be given soon after meals. Adjustment of dosage may also be necessary if patients undertake increased physical activity or change their usual diet.
Date of revision of the text. Insulin lispro maintains more rapid absorption and elimination when compared to soluble human insulin in patients with hepatic impairment. Within muscle hukalog this includes increasing glycogen, fatty acid, glycerol and protein synthesis and amino acid uptake, while decreasing glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism and amino acid output.
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It is essential to maintain good control of the insulin-treated insulin-dependent or gestational diabetes patient throughout pregnancy. For the full list of excipients, see section 6. Show table of contents Hide table of contents 1. Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness. A few patients who have experienced hypoglycaemic reactions after transfer from animal-source insulin to human insulin have reported bulw the early warning symptoms of hypoglycaemia were less pronounced or different from those experienced with their previous insulin.
Insulin lispro did not induce fertility impairment, embryotoxicity or teratogenicity in animal studies.
Patients must be educated to use the proper injection techniques. Ideal for people with no prescription coverage,or drug is not covered The patient should discard the needle after every injection. Healthcare professionals are asked to report any suspected adverse reactions via Ireland: In some instances, this condition may be related to factors other than insulin, such as irritants in the skin cleansing agent or poor injection technique.
Excipients This medicinal product contains less than 1 mmol sodium 23 mg per dose, i.